BRCA1 and neoplasm: Some of the dysregulated ASEs that were identified include CD44, which encodes a cell-surface protein implicated in cell-cell interactions, migration, and cell adhesion and which has previously been involved in tumor metastasis and GC [17], and BRCA1 which encodes a nuclear protein involved in genomic stability which also functions as a tumor suppressor and is frequently mutated in breast and ovarian cancers.