Wang et al. (23)reported that miR-181b inhibited glioma cell proliferation by targeting cyclin B1.Pekarsky et al. (24) reported that the expressionlevels of Tcl1 are inversely correlated with miR-181 expression and that Tcl1 expressionis regulated by miR-181 in chronic lymphocytic leukemia, but the role of miR-181b hasnot been described in BL. This evidence concerns the gene CCNB1 and B-cell chronic lymphocytic leukemia.