In thispotential mechanism, low expression of mir-181b leads to dysregulation ofFAMLF, and overexpression of FAMLF may up-regulateexpression of genes related to cell proliferation, such as c-MYC,through transcription factor activity, resulting in uncontrolled cell proliferation,which may be an important mechanism of the pathogenesis of BL. This evidence concerns the gene MYC and Burkitt lymphoma.