To understand the effects of CTS on the characterization of mouse glioma, we then detected the expression of phosphorylated STAT3 Tyr705, Ki67 and glial fibrillary acidic protein (GFAP), an indicator for reactive gliosis in the brain tissue adjacent to the tumor by immunohistochemistry in paraffin-embedded glioma sections. The gene discussed is STAT3; the disease is neoplasm.