However, the inducible PLSCR1 is predominantly localized outside nuclei with little distribution in the nucleus.12 Nuclear trafficking of newly expressed PLSCR1 has been observed only following transcriptional activation by IFN.30 Here, we found that PLSCR1 expression was increased by wogonoside (150 μM) in primary AML cells derived from 13 samples (the 13 samples include #2, #4, #5, #6, #10, #13, #14, #16, #17, #18, #19, #20 and #21 samples) in all 23 peripheral blood samples of AML patients. This evidence concerns the gene PLSCR1 and acute myeloid leukemia.