Worldwide, morbidity and mortality of cervical cancer (CaCx) rank fourth in cancers ofwomen.23, 24 It is well accepted that human papillomavirus (HPV) infection ishighly correlated with cervical cancer.25, 26 Loss of GJIC and reduction of expression of Cx26,Cx30 and Cx43 were described in HPV-infected dysplastic cervical epithelialcells.27, 28 However, these reports are based primarily on in vitroor animal experiments; data on expression and distribution of Cx in human CaCx specimensare rare. The gene discussed is GJA1; the disease is cervical cancer.