In addition to “traditional” PD mutations (such as A53T3, A30P143, and E46K144) that have been known to the scientific community for a relatively long time, several “new” disease-associated mutations in α-synuclein (H50Q145,146, G51D147,148, and A53E149) were discovered over the past 3 years. This evidence concerns the gene SNCG and Parkinson disease.