Anti-Dengue IgM antibodies generally persist for 2–6 months (3, 9–11) whereas anti-Dengue IgG antibodies appear after IgM approximately at day 7 of the fever (3, 7, 11, 12) in primary dengue infections but sometimes even as late as day 18 of hospitalization (6) and persists for a long time (7, 11). Here, CD40LG is linked to dengue disease.