While serum levels of IFN-γ, IL-2, IL-4, and IL-12 did not display a difference between experimental groups (data not shown), expression of IL-5, IL-6, TNF-α, IL-10, CXCL1, and IL-1β was elevated in the NZM2410/J mice displaying signs of severe kidney damage (Figure 3). The gene discussed is CXCL1; the disease is Nephropathy.