Adiponectin may attenuate TNF-α, IL-6, MCP-1, vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and endothelial-leukocyte adhesion molecule 1 (ELAM-1) expression, inflammation, oxidation, and fibrosis in AT through the inhibition of NF-kB activation [69–71]. The gene discussed is ICAM1; the disease is ataxia telangiectasia.