AKT1 and cervical carcinoma: Initially, to test if the inhibitory activity of Zey on cervical carcinoma cells was associated with abrogation of PI3K/AKT/mTOR pathways, phosphorylation of PI3K, and corresponding signals AKT, mTOR, and P70S6K were detected by western blot analysis after cells were exposed to Zey for 24 h.