SOD1 and amyotrophic lateral sclerosis: Moreover, C57BL/6 mice expressing human SOD1 (hSOD1) with the ALS‐linked G93A mutation (hereafter ALS mice) manifest progressive muscle paralysis similar to that observed in clinical cases along with the histopathological hallmarks observed in familial and sporadic ALS, including NMJ defects (Dadon‐Nachum et al, 2011; Zhu et al, 2015).