From the clinicopathological point of view, they are divided into as somatotroph adenomas, which produce growth hormone; lactotroph adenomas, which produce prolactin; thyrotroph adenomas, which produce thyroid-stimulating hormone (TSH); corticotroph adenomas, which produce adrenocorticotropic hormone ACTH); and gonadotroph adenomas, which produce gonadotropin [1]. This evidence concerns the gene GH1 and familial isolated pituitary adenoma.