Enforced SOX2OT expression was predictive of unfavorable OS (HR = 2.44, 95% CI: 1.75–3.39, P<0.0001) and tumor progression (III/IV vs. I/II: HR = 1.62, 95% CI: 1.30–2.02, P<0.0001) in various carcinomas with multivariate analysis, respectively (Figs 2 and 3). Here, SOX2-OT is linked to carcinoma.