TP53 and neoplasm: The tumour suppressor gene p53 was mutated in 65/118 (55%) tumour samples and in total 77 mutations occurred: R248Q in 7 ATCs; T125A, R209fs, P278S and R280T in 5 ATCs; S183* and R273C in 3 ATCs each; and C135F, Y220C, G266E, V272L, R282W and E285K in 2 ATCs each (Supplementary Table 1).