Furthermore the group of Xing M et al. showed that coexisting BRAF V600E and TERT C228T alterations in papillary thyroid carcinoma (PTC) are associated with a significantly higher risk of recurrence and poorer outcome as well as older age and distant metastasis in ATC [9, 13]. The gene discussed is BRAF; the disease is thyroid gland papillary carcinoma.