Among the 92 genes, 10 genes including BUB1B, CCNB2, CDC25C, CDKN2A, COL11A1, FAM111B, MKI67, NDC80, NEK2 and TTK have previously been identified to be cancer driver genes via NCG 5.0 [42] (Supplementary Table 2). The gene discussed is TTK; the disease is cancer.