Such anti-tumour efficacy ofATF5-CaP-rHDL was further confirmed in the patient-derived xenograft mice model.As shown in Fig. 9b, compared with that in saline-treatedanimals, the expression of ATF5 at the centre of tumour site was inhibited by80% following the ATF5-CaP-rHDL treatment. This evidence concerns the gene ATF5 and neoplasm.