We next investigated the mutation data for 24 important genes (TP53, VHL, PBRM1, SETD2, KDM5C, BAP1, NF2, PTEN, ARID1A, MICALCL, STAG2, SLC1A3, CDKN1A, MTOR, MET, SMARCB1, TCEB1, NFE2L2, PIK3CA, MLL3, FH, FLCN, TSC1, TSC2) recurrently mutated in the three TCGA kidney cancer subtypes based on the three TCGA kidney cancer studies17, 22, 24. Here, SETD2 is linked to kidney cancer.