We next investigated the mutation data for 24 important genes (TP53, VHL, PBRM1, SETD2, KDM5C, BAP1, NF2, PTEN, ARID1A, MICALCL, STAG2, SLC1A3, CDKN1A, MTOR, MET, SMARCB1, TCEB1, NFE2L2, PIK3CA, MLL3, FH, FLCN, TSC1, TSC2) recurrently mutated in the three TCGA kidney cancer subtypes based on the three TCGA kidney cancer studies17, 22, 24. This evidence concerns the gene PBRM1 and kidney cancer.