To date, increased levels of IFN-γ are used to explain a good outcome by upregulating the MHC class I of tumour cells, targeting endothelium and inhibiting neoangiogenesis, activating M1 macrophages and NK cells, enhancing antitumour Th1 immune response, and directly inducing tumour cell apoptosis51. The gene discussed is IFNG; the disease is neoplasm.