The pooled HRs of cumulative meta-analysis(Figure 6) ranged from 1.23(95%CI: 1.06-1.42) to 1.27 (95%CI: 1.04-1.56) for OS since 2013, demonstrating that performance of Ki-67 expression for OS in GC patients was stable and reliable. The gene discussed is MKI67; the disease is gastric cancer.