We also measured the concentration of several putative cytokines (IL-1β, IL-2, IL-4, IL-6, IL-8, IL-18, IFN-γ and TNF-α) and growth factors (vascular endothelial growth factor, VEGF, hepatocyte growth factor, HGF and, basic fibroblast growth factor, bFGF) in AML cell conditioned media and studied the effects of adding recombinant cytokines and neutralizing antibodies on cellular LDL degradation. This evidence concerns the gene IL4 and acute myeloid leukemia.