TP53 and urinary bladder neoplasm: GEMs for bladder tumors include those with altered pRB and/or p53 [31, 32]; Pten with or without p53 [33, 34]; Kras and Hras [35, 36]; Egfr [37]; p21 [35]; IL17, IL12, IL23, and IFNγ [38–40]; and others [2–4].