ADAM17 and infection: Interesting is that either conditional ADAM17 knockout mice or hematopoietic chimeric mice that lacked ADAM17 in leukocytes demonstrated accelerated neutrophil recruitment at sites of sterile inflammation as well as infection (Long et al., 2010, 2012; Arndt et al., 2011; Tang et al., 2011; Mishra et al., 2015, 2016).