Similar to the findings for the acute stage of infection, the five pathways related to TLR4/TLR3 also presented in the top 10 enriched pathways in the chronic stage of infection, including “TLR4 cascade,” “activated TLR4 signaling,” “TRIF-mediated TLR3/TLR4 signaling,” “MyD88-independent cascade,” and “TLR3 cascade.” We extracted a subnetwork that contained all nodes that are involved in these five pathways (Table S3 in Supplementary Material; Figure 2). This evidence concerns the gene MYD88 and infection.