FOS and acute respiratory distress syndrome: Moreover, CQCQD has a protective effect in SAP complicated with acute lung injury (ALI) and acute respiratory distress syndrome by inhibiting ER stress in AMs, attenuating pro-inflammatory cytokine release and paracellular leakage, which involved in the down-regulation of p-Src, p-p85α, and c-Fos (Wang Z.C. et al., 2009; Jia et al., 2015; Wu W.U. et al., 2016).