Research has indicated that the mTOR/p70s6k signaling pathway was activated in esophageal squamous cell carcinoma and rapamycin, suppressed mTOR expression and phosphorylation of p70s6k, arrested cell cycle at the G0/G1 phase, and induced apoptosis of EC cells [22]. Here, RPS6KB1 is linked to esophageal squamous cell carcinoma.