Gene expression in tumor EPCAM+CD44+CD49f+ cells further segregated intratumoral from lymph node EPCAM+CD44+CD49f+ cells with 381 genes differentially expressed, including upregulation of genes involved in immune responses and cell adhesion (Gene Ontology) in lymph node EPCAM+CD44+CD49f+ cells (Supplementary Figure 4). The gene discussed is ITGA6; the disease is neoplasm.