For p-tau levels in iNPH versus AD, the pooled SMD was −2.03 (95% CI −2.77 to −1.30, P < 0.00001) in lumbar CSF groups and −0.12 (95% CI −0.41 to 0.17, P = 0.42) in ventricular CSF groups. This evidence concerns the gene MAPT and Alzheimer disease.