MAPK1 and frontotemporal dementia: Trifluridine also induced p38 MAPK phosphorylation (Fig. 4B, Table 1), which was not affected by either panitumumab or erlotinib, suggesting that upstream signaling through p38 MAPK phosphorylation and ERK/AKT/STAT3 phosphorylation was differentially induced by FTD.