As the MEK inhibitor U0126 blocked FTD‐induced AKT/ERK/STAT3, EGFR T669, and S1046/1047 phosphorylation to a similar extent as panitumumab, the effect of cotreatment with FTD and the MEK inhibitors U0126 or trametinib on cell proliferation was evaluated. This evidence concerns the gene EGFR and frontotemporal dementia.