The shutting down of host RNAP is crucial for the successful completion of the infection cycle: Gp0.7 is a protein kinase that phosphorylates the Ec RNAP, leading to increased termination of transcription at sites located between the early and middle genes on the T7 genome (6); and Gp2 binds in the main DNA binding channel in Ec RNAP and thereby prevents the formation of the transcriptionally proficient open promoter complex (RPo) at the T7 A1-3 promoters (7). Here, GP2 is linked to infection.