Worth to note, CNAs of 37 genes were exclusively found in G3 tumours such as WNT7B (4 gains), BAD (3 gains), WEGFB (3 gains) and HDAC2 (3 losses) in respect to 65 CNA genes exclusively presented in G1 tumours, such as GRB2 (5 losses) and FGF21, STAT3, CTNNA3 and DVL3 with 3 losses each. The gene discussed is GRB2; the disease is neoplasm.