Regarding CNAs present in 419 tumour suppressor genes (Table C in S2 File), losses of the most common CNA tumour suppressor genes are found at 3p21.31 specified by genes RBM6 in 35 HRO-, RBM5 in 30 HRO-, LIMD1 in 28 HRO-, TCTA in 26 HRO- and at 3p22.2 by MLH1 in 33 HRO-tumours. This evidence concerns the gene MLH1 and neoplasm.