Gains of 4 tumour suppressor genes such as PAX4 at 7q32.1, NAPEPLD, ARMC10, and FBXL13 at 7q22.1 were determined in 4/20 G3 tumours as well as 5 single gene gains at loci at 1q21.2 (PLEKHO1), 11q13.1 (PLCB3), 12p13.1 (EMP1), 18p11.21 (PTPN2), and 19p13.3 (PLK5) additionally present in 5/20 G3 tumours exclusively specifying Fuhrman G3 tumours (S1 Table). This evidence concerns the gene PLEKHO1 and neoplasm.