Chromosomal losses and gains regarding 254 driver genes analysed determined losses of SETD2 (43/48) and MAP4 (38/48) at 3p21.31 assigned to Fuhrman grade G1 in 24/26 G1 and 23/26 G1 tumours, respectively, to 17/20 G3 and 13/20 G3 tumours. The gene discussed is MAP4; the disease is neoplasm.