IL6 and Sepsis: In the present study, neonates with EOS had a significantly lower level of 25-OH D (preterm 5.5 ± 2.27 nmol/L), (full term 7.3 ± 6.18 nmol/L) when compared to healthy control groups of neonates (p < 0.001) agreeing with the results of Leo et al. [14], and there were strong significant negative correlations between 25-OH vitamin D and all sepsis markers like (I/T ratio, CRP and IL-6).