Similar to our results, YY1 is overexpressed in most cancers, such as breast cancer 16, prostate carcinoma 27, ovarian cancer 28, brain cancer 29, acute myeloid leukemia 30, osteosarcoma 31, gastrointestinal cancer 32, cervical cancer 33, and hepatoblastoma 34. The gene discussed is YY1; the disease is acute myeloid leukemia.