RORC and bacterial infectious disease: Bacterial infection was carried out as above, in flies bearing MARCM clones homozygous for null alleles of InR, Pi3K, or TOR. In contrast to the results obtained in noninfected flies, these mutant clones contained many cells, and the ECs in these clones had high ploidies similar to those in ECs from stressed wild-type controls (Fig. 3e,h and Supplementary Fig. 4e).