Furthermore, in some studies, a synergistic effect for phosphorylation between c-MET and epidermal growth factor receptor (EGFR), HER2, HER3, RAS, RON, or PDGFR was found in some cancer cells or transfected cancer cells, and these studies might have important significance for combination therapy in many cancers [27–32]. This evidence concerns the gene PDGFRB and cancer.