Allgrove syndrome may be referred to with respect to the relation between achalasia and the genes, which is an autosomal recessive disease with three signs, achalasia, alacrima, and adrenocortical insufficiency complicated by muscular atrophy and muscle weakness, and was first reported in 1978 by Allgrove et al. [4] The ALADIN gene has been identified as the responsible gene [5–8]. Here, AAAS is linked to Achalasia.