FH and hereditary leiomyomatosis and renal cell cancer: Other TCA cycle enzymes involved in cancer are succinate dehydrogenase (SDH) in hereditary paragangliomas [28–31] and gastrointestinal stromal tumour (GIST) [32], and fumarate hydratase (FH) in hereditary leiomyomas and renal cell cancer (HLRCC) [33].