Leukemia-associated antigen (LAA)-specific CTLs have been detected in the peripheral blood of CP CML patients, including CTLs specific for Bcr-abl and selectively expressed or overexpressed LAAs such as proteinase-3 (PR3) and Wilms’ tumor antigen 1 (WT1), and may be involved in the immunological control of CML (49–51). The gene discussed is PRTN3; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.