Since we previously demonstrated that increased ICAM-1 and fibronectin adhesion of HSV-1-infected mDCs is based on the induced β2-integrin activity (45), we next examined the activation status of β2-integrins after HCMV infection using an antibody which recognizes a conformational epitope only present on activated β2-integrins (56–58). This evidence concerns the gene ICAM1 and cytomegalovirus infection.