RHD and rhabdomyosarcoma: Treatment of mice bearing rhabdomyosarcoma xenografts Rh18 (Fig. 1A) and Rh30 (Fig. 1B), with AZD8055 potently inhibited both mTORC1 and mTORC2 as demonstrated by the absence of pS6-S235/236 and pAKT-S47327.