Animals infected with LM-PLP exhibited reduced clinical disease scores when compared to the other treatment groups, as evidenced by their reduced CDI (38.3 ± 2.9 vs. 51.5 ± 3.7, 49.9 ± 2.6; p < 0.01) (Fig. 4A). The gene discussed is PLP1; the disease is clostridium difficile infection.