PLP1 and clostridium difficile infection: Mice that received CD8 T cells from LM-PLP infected donors exhibited significantly reduced peak disease scores (1.5 ± 0.2 vs. 3.3 ± 0.4, p < 0.01) and CDI (17.8 ± 2.2 vs. 48.4 ± 5.4, p < 0.001), in comparison to LM-OVA controls (Fig. 2D).