The rs5743551 (−7202G>A) variation in the TLR1 gene, the rs7656411 (22215G>T) variation in the TLR2 gene and the rs11536889 (+3725G>C) variation in the TLR4 gene were genotyped in 365 recipients with hematologic malignancies and their unrelated donors in the discovery cohort (Table 1). Here, TLR4 is linked to hematologic disorder.