On preliminary univariate analysis, age, initial PSA ≥ 20 ng/mL, pathologic Gleason sum 7, ≥8, pathologic T stage 3, 4, PSM, lymph node metastasis and LVI showed statistically significant difference in BCR risk, as shown in Table 2. This evidence concerns the gene BCR and metastatic malignant neoplasm in the lymph nodes.