Elevated PSA above 20 ng/mL (OR 3.208 95% CI 1.647–6.246, p = 0.001) and PSM (OR 3.697, 95% CI 1.462–9.351, p = 0.006) were also associated with lymph node metastasis. Here, KLK3 is linked to metastatic malignant neoplasm in the lymph nodes.