Following adjustment for age, sex, time on hemodialysis, body mass index, primary kidney disease, atherosclerotic heart disease, congestive heart failure, cerebrovascular accident/TIA, diabetes, serum albumin, and baseline physical activity, the hazard ratios for all-cause mortality in the becoming less active group and stable group were 2.73 (95% CI: 1.12–6.62; P = 0.03) and 1.41 (95% CI: 0.53–3.67; P = 0.49), respectively, compared to the becoming more active group (Model 1). This evidence concerns the gene ALB and transient ischemic attack.