In contrast, Subhawong in 2009 [67] established a similarity between the immunophenotypic characteristics of triple-negative tumors (and more specifically of basal-like tumors) and HPV-positive squamous cell carcinomas (functional loss of the retinoblastoma tumor suppressor, presence of p16 or p53 overexpression). This evidence concerns the gene TP53 and squamous cell carcinoma.