POLG and Wilson disease: Other neurogenetic disorders, such as Fragile X-associated tremor/ataxic syndrome, MSA-C, Wilson’s disease, mitochondrial recessive ataxia syndrome with mutations in POLG, cerebrotendinous xanthomatosis, Krabbe disease, and peroxisomal disorders may also manifest with cerebellar ataxia accompanied by WMH in the cerebellum [1, 49, 50].