Multivariate analysis including the variables CD34+ cell dose, day of engraftment, GvHD Prophylaxis, ANC <15 days vs ⩾15, F-araA AUC >29.4 vs <29.4 μm × h, diagnosis (FA or AA), donor source as well the polymorphisms rs2295890, rs491799 on the incidence of acute GvHD showed F-araA AUC >29.4 μm × h to be significant factor (P=0.02). The gene discussed is CD34; the disease is graft versus host disease.