Interestingly, endothelial cells stimulated with TNF-α, which is overproduced during inflammation in MS [23], resulted in much higher VCAM-1 expression than IL-17 stimulation, while increased VCAM-1 expression was also noted following stimulation with a combination of TNF-α and the lowest concentration of IL-17 [24]. The gene discussed is VCAM1; the disease is myeloid sarcoma.