Additionally, we identified other metabolism related genes including tk1 (lower expressed in HQJE male), xdh (higher expressed in HQJE male), a Phytanoyl-CoA dioxygenase domain containing gene (zgc:174917; higher expressed in HQJE male) and a CNDP dipeptidase 2 ortholog gene (zgc:114181; lower expressed in HQJE male); diabetes related gene socs3a (higher expressed in HQJE male); as well as energy and lipid related genes mogat3a (higher expressed in HQJE male) and pnrc2 (lower expressed in HQJE male). The gene discussed is PNRC2; the disease is diabetes mellitus.