Of these potential binding partners, we focused on EGL-19/Cav1 because human CACNA1C (which encodes a Cav1 α-subunit) is mutated in Timothy Syndrome (TS), a rare monogenic form of ASD (Splawski et al., 2005, 2004), and polymorphisms linked to CACNA1C are associated with multiple psychiatric disorders (Cross-Disorder Group of the Psychiatric Genomics Consortium, 2013). This evidence concerns the gene CAV1 and psychiatric disorder.