NFKB1 and Miyoshi myopathy: Since RKIP expression regulates both the NF-κB and MAPK survival pathways, the overexpression of “inactive” p-Ser153 RKIP in MM might contribute positively to the overall cell survival/antiapoptotic phenotype and drug resistance of MM through the constitutive activation of survival pathways and the downstream transcription of anti-apoptotic gene products, which can contribute to the overall cell survival and drug resistance [11, 60]